Stochastic vesicle-state model of short-term dynamics at a single synaptic active zone. (a) A single simulation run, showing the release probability p, the actual number of releasable vesicles, n (initially 1), and neurotransmitter release, T. (b) Average values of these variables, taken over 10000 trials. Phenomenological model of facilitation: p_{0} = 0.2; Δp = 0.05; τ_{f} = 100 ms. Vesicle-state model: k^{∗}_{n} = k_{r} = 0.2 s^{−1}; n_{s} = 0.1. Synapse stimulated at 50Hz.

# Figure 7.11

Stochastic model of short-term synaptic dynamics

Simulation environment:

Notes

Unzip file and run *runsynnp_rvs.m* in MATLAB. Results may not be identical to the figure as this is a stochastic model and the results depend on the random number generator and its seed.

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