Cell signalling

Repositories of cell signalling pathway models are available. Certain data relevant to the specification of parameter values in such models are also available. Protein interaction databases are useful for developing signalling schemes. Typically little reaction rate data is available. Enzymatic kinetics are generally more readily available.

Published cell signalling models for a variety of simulation environments. Links to associated data sources are provided. Models can be run online via the simulation environment JWS Online (http://jjj.biochem.sun.ac.za/index.html). http://www.ebi.ac.uk/biomodels/
BJP Guide to Receptors and Channels:
An overview of receptors and channels with bibliographies for each channel subfamily. http://www.nature.com/bjp/journal/vgrac/ncurrent/
The Database of Quantitative Cellular Signalling contains models of signalling pathways, largely built using GENESIS and Kinetikit. It includes reaction schemes, concentrations and rate constants. http://doqcs.ncbs.res.in/
IUPHAR Databases:
The IUPHAR Database of G-Protein-Coupled Receptors and the IUPHAR Database of Voltage-Gated and Ligand-Gated Ion Channels contain information about the gene sequences, structural and functional characteristics and pharmacology of ion channels. They are available from the database of the IUPHAR Committee on Receptor Nomenclature and Drug Classification. http://www.iuphar-db.org/