Three distinct trials of a complete synapse model with 500 independent active zones. Each active zone uses the stochastic vesicle-state model of short-term synaptic dynamics combined with the 2-gate kinetic model of AMPA receptors. Phenomenological model of facilitation: p_{0} = 0.2; Δp = 0.05; τ_{f} = 100 ms. Vesicle-state model: k^{∗}_{n} = k_{r} = 0.2 s^{−1}; n_{s} = 0. 2-gate kinetic receptor model: α = 4 mM^{−1}ms^{−1}, β = 1 ms^{−1}. E_{syn} = 0 mV, with postsynaptic cell clamped at −65 mV. Synapse stimulated at 100Hz.

# Figure 7.12

Complete stochastic synapse model

Simulation environment:

Notes

A different result appears each time you run the simulation, since it is a stochastic model.

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