Calcium transients in (a) the potassium channel colocalised pool, (b) the larger submembrane shell, (c) the compartment core in a three pool model. Note that in (a) the concentration is plotted on a different scale. Compartment 1 μm in diameter with 0.1 μm thick submembrane shell; colocalised membrane occupies 0.001% of the total membrane surface area. Calcium influx into the colocalised pool. Calcium current, diffusion and membrane-bound pump parameters as in Figure 6.5.